Ibuprofen and Naproxen May Cause Miscarriage

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New study data suggests that women who take ibuprofen while pregnant are more than twice as likely to miscarry as those who don’t. The study, according to Reuters, included pain killers that are non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil and Motrin), naproxen (Aleve and Naprosyn) and the arthritis drug, celecoxib (Celebrex).

The study was reported in the Canadian Medical Association Journal. The senior researcher on the study, Anick Berard, is with the University of Montreal’s CHU Sainte-Justine Research Center. Berard’s research theorizes that miscarriage is caused by NSAIDs interference with changes in early pregnancy hormone-like substances called prostaglandins. Prostaglandin production naturally declines in the uterus during early pregnancy. According to Berard, because NSAIDs affect prostaglandin production, this process is disturbed, leading to miscarriage.

Although all medications are generally discouraged for pregnant women, some women have chronic conditions to treat such as arthritis and lupus. Berard says that these types of chronic conditions usually improve during pregnancy, allowing pregnant women to suspend those medications. For general, short-term pain relief such as back pain or headaches, Berard advises women to use Tylenol, if anything. Miscarriages sometimes happen before women know they’re pregnant, so Berard advises women who are planning pregnancy the same way.

The effect is not proven with the study, as there are other factors in the sample population that might also contribute to miscarriage. However, there is some past research that also indicates miscarriages caused by NSAID use. Also, the study results make a compelling case overall with NSAID use tied to a 2.4-times higher risk of miscarriage. Typically, pregnant women have a 15 percent chance of a miscarriage that occurs after a woman knows she is pregnant.

If you or your loved one has suffered an injury due to a dangerous drug, you may be able to take legal action..