Proton Pump Inhibitors

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Americans who take high doses of popular ulcer and acid reflux drugs such as Nexium®, Prevacid®, and Prilosec® for a more than year face a possible increased risk of broken bones, including fractures of the spine, hip, arm, and leg, warns the Food and Drug Administration (FDA).

Nexium (esomeprazole), Prevacid (lansoprazole), and Prilosec (omeprazole) belong to a class of drugs known as proton pump inhibitors, or PPIs.

PPIs work by reducing the amount of stomach acid and are approved to treat conditions such as gastroesophageal reflux disease (GERD), stomach and small intestine ulcers, and inflammation of the esophagus. Other PPIs include: Aciphex® (rabeprazole); Protonix® (pantoprazole); Zegarid® (a rapid-release form of Prilosec); Dexilant® (dexlansoprazole); Vimovo® (naproxen and esomeprazole).

The FDA’s warning is based on its review of several studies that reported an increased risk of fractures of the hip, wrist, and spine with PPI use, particularly in patients 50 years and older. The agency is revising the prescription and over-the-counter (OTC) labels for this class of drugs to make patients and doctors aware of the risk.

If you or your loved one has suffered a Proton Pump Inhibitor injury, contact us today. Submit the form to the right and we’ll let you know if you have a case and if we can represent you.